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Latent Space: The AI Engineer Podcast

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Latent Space: The AI Engineer Podcast
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  • ⚡ Inside GitHub’s AI Revolution: Jared Palmer Reveals Agent HQ & The Future of Coding Agents
    Jared Palmer, SVP at GitHub and VP of CoreAI at Microsoft, joins Latent Space for an in-depth look at the evolution of coding agents and modern developer tools. Recently joining after leading AI initiatives at Vercel, Palmer shares firsthand insights from behind the scenes at GitHub Universe, including the launch of Agent HQ which is a new collaboration hub for coding agents and developers. This episode traces Palmer’s journey from building Copilot inspired tools to pioneering the focused Next.js coding agent, v0, and explores how platform constraints fostered rapid experimentation and a breakout success in AI-powered frontend development. Palmer explains the unique advantages of GitHub’s massive developer network, the challenges of scaling agent-based workflows, and why integrating seamless AI into developer experiences is now a top priority for both Microsoft and GitHub.
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  • ⚡ [AIE CODE Preview] Inside Google Labs: Building The Gemini Coding Agent — Jed Borovik, Jules
    Jed Borovik, Product Lead at Google Labs, joins Latent Space to unpack how Google is building the future of AI-powered software development with Jules. From his journey discovering GenAI through Stable Diffusion to leading one of the most ambitious coding agent projects in tech, Borovik shares behind-the-scenes insights into how Google Labs operates at the intersection of DeepMind's model development and product innovation. We explore Jules' approach to autonomous coding agents and why they run on their own infrastructure, how Google simplified their agent scaffolding as models improved, and why embeddings-based RAG is giving way to attention-based search. Borovik reveals how developers are using Jules for hours or even days at a time, the challenges of managing context windows that push 2 million tokens, and why coding agents represent both the most important AI application and the clearest path to AGI. This conversation reveals Google's positioning in the coding agent race, the evolution from internal tools to public products, and what founders, developers, and AI engineers should understand about building for a future where AI becomes the new brush for software engineering. Chapters 00:00:00 Introduction and GitHub Universe Recap 00:00:57 New York Tech Scene and East Coast Hackathons 00:02:19 From Google Search to AI Coding: Jed's Journey 00:04:19 Google Labs Mission and DeepMind Collaboration 00:06:41 Jules: Autonomous Coding Agents Explained 00:09:39 The Evolution of Agent Scaffolding and Model Quality 00:11:30 RAG vs Attention: The Shift in Code Understanding 00:13:49 Jules' Journey from Preview to Production 00:15:05 AI Engineer Summit: Community Building and Networking 00:25:06 Context Management in Long-Running Agents 00:29:02 The Future of Software Engineering with AI 00:36:26 Beyond Vibe Coding: Spec Development and Verification 00:40:20 Multimodal Input and Computer Use for Coding Agents
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  • Priscilla Chan and Mark Zuckerberg: Frontier AI + Virtual Biology To Solve All Diseases
    Today’s guests are Priscilla Chan and Mark Zuckerberg, co-founders of Biohub (fka Chan Zuckerberg Initiative). They are one of the leading institutes for AI x Bio and open science research with projects like CELLxGENE, rbio1, VariantFormer, and many more. We talked about the evolution from a broad philanthropic institute to specializing in frontier AI + bio, why they are building 12ft tall microscopes to gather better data, and how building a virtual cell model + virtual immune system could potentially help us cure all diseases. Chapters 00:00:00 Introduction and CZI's 10-Year Anniversary 00:00:56 Learning from Bill Gates 00:04:05 Science vs Translation 00:10:45 The Power of Physical Proximity in Science 00:13:55 Building the Virtual Cell: From Data to Models 00:15:51 Microscopes, Imaging, and Converting Atoms to Bits 00:23:18 AI Meets Biology: The Frontier Lab Concept 00:27:25 How Models Can Enable More Ambitious Research 00:30:15 Precision Medicine and Clinical Impact 00:45:17 The Virtual Immune System and Cellular Engineering 00:48:27 Accelerating the Timeline: What It Takes to Cure All Disease 00:28:45 Joining Forces with Evolutionary Scale
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  • How Zyphra went all-in on AMD + Why Devs feel faster with AI but are slower — with Quentin Anthony
    OpenAI recently made waves by being the first big model lab to commit to a hyperscale AMD cluster (together with their own Titan XPUs), giving AMD the first biglab silicon win outside of Nvidia/Google. Returning guest Quentin Anthony, Head of Model Training at Zyphra and advisor at EleutherAI, has recently done this same transition. In part 1 of this pod, Quentin describes his journey from working on Oak Ridge National Lab's Frontier supercomputer to leading Zyphra's ambitious move to AMD MI300X GPUs, where they're achieving performance that beats NVIDIA H100s on certain workloads while dramatically reducing costs. The discussion dives deep into the technical challenges of kernel development, with Quentin explaining why he often bypasses high-level frameworks like Triton to write directly in ROCm or even GPU assembly when necessary. He reveals how Zyphra's hybrid transformer-Mamba models like Zamba 2 can match Llama 3 8B performance at 7B parameters, optimized specifically for edge deployment across a spectrum from 1.2B models for phones to 7B for desktops. In Part 2, Quentin then candidly discusses his experience in the controversial METR software engineering productivity study, which found that developers felt 20% faster while using AI coding tools, but were in fact 20% slower. Quentin was one of the few developers who showed measurable speedup from AI tools. He shares practical insights on avoiding the "slot machine effect" of endlessly prompting models, the importance of context rot awareness, and why he prefers direct API access over tools like Cursor to maintain complete control over model context. The conversation also covers the state of open source AI research, with Quentin arguing that siloed, focused teams with guaranteed funding produce better results than grand collaborative efforts. He explains why kernel datasets alone won't solve the GPU programming problem, the challenges of evaluating kernel quality, and why companies should invest more in ecosystem development rather than traditional marketing. https://www.linkedin.com/in/quentin-anthony/ https://www.zyphra.com/post/zamba2-7b Key Topics: • AMD MI300X advantages: 192GB VRAM, superior memory bandwidth • Writing kernels from PTX/AMD GCN assembly up through CUDA/ROCm • Hybrid attention-Mamba architectures and optimal sparsity ratios • The Menlo productivity study: achieving positive AI speedup • Context rot and why shorter conversations beat long threads • Why physicists make great ML engineers ("embryonic stem cells") • Edge deployment strategies from phones to local clusters • The future of on-device vs cloud inference routing • EleutherAI's focus on interpretability with fully open pipelines • Building velocity-focused teams over position-based hiring
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  • ⚡️ Ship AI recap: Agents, Workflows, and Python — w/ Vercel CTO Malte Ubl
    In this conversation with Malte Ubl, CTO of Vercel (http://x.com/cramforce), we explore how the company is pioneering the infrastructure for AI-powered development through their comprehensive suite of tools including workflows, AI SDK, and the newly announced agent ecosystem. Malte shares insights into Vercel's philosophy of "dogfooding" - never shipping abstractions they haven't battle-tested themselves - which led to extracting their AI SDK from v0 and building production agents that handle everything from anomaly detection to lead qualification. The discussion dives deep into Vercel's new Workflow Development Kit, which brings durable execution patterns to serverless functions, allowing developers to write code that can pause, resume, and wait indefinitely without cost. Malte explains how this enables complex agent orchestration with human-in-the-loop approvals through simple webhook patterns, making it dramatically easier to build reliable AI applications. We explore Vercel's strategic approach to AI agents, including their DevOps agent that automatically investigates production anomalies by querying observability data and analyzing logs - solving the recall-precision problem that plagues traditional alerting systems. Malte candidly discusses where agents excel today (meeting notes, UI changes, lead qualification) versus where they fall short, emphasizing the importance of finding the "sweet spot" by asking employees what they hate most about their jobs. The conversation also covers Vercel's significant investment in Python support, bringing zero-config deployment to Flask and FastAPI applications, and their vision for security in an AI-coded world where developers "cannot be trusted." Malte shares his perspective on how CTOs must transform their companies for the AI era while staying true to their core competencies, and why maintaining strong IC (individual contributor) career paths is crucial as AI changes the nature of software development. What was launched at Ship AI 2025: AI SDK 6.0 & Agent Architecture Agent Abstraction Philosophy: AI SDK 6 introduces an agent abstraction where you can "define once, deploy everywhere". How does this differ from existing agent frameworks like LangChain or AutoGPT? What specific pain points did you observe in production that led to this design? Human-in-the-Loop at Scale: The tool approval system with needsApproval: true gates actions until human confirmation. How do you envision this working at scale for companies with thousands of agent executions? What's the queue management and escalation strategy? Type Safety Across Models: AI SDK 6 promises "end-to-end type safety across models and UI". Given that different LLMs have varying capabilities and output formats, how do you maintain type guarantees when swapping between providers like OpenAI, Anthropic, or Mistral? Workflow Development Kit (WDK) Durability as Code: The use workflow primitive makes any TypeScript function durable with automatic retries, progress persistence, and observability. What's happening under the hood? Are you using event sourcing, checkpoint/restart, or a different pattern? Infrastructure Provisioning: Vercel automatically detects when a function is durable and dynamically provisions infrastructure in real-time. What signals are you detecting in the code, and how do you determine the optimal infrastructure configuration (queue sizes, retry policies, timeout values)? Vercel Agent (beta) Code Review Validation: The Agent reviews code and proposes "validated patches". What does "validated" mean in this context? Are you running automated tests, static analysis, or something more sophisticated? AI Investigations: Vercel Agent automatically opens AI investigations when it detects performance or error spikes using real production data. What data sources does it have access to? How does it distinguish between normal variance and actual anomalies? Python Support (For the first time, Vercel now supports Python backends natively.) Marketplace & Agent Ecosystem Agent Network Effects: The Marketplace now offers agents like CodeRabbit, Corridor, Sourcery, and integrations with Autonoma, Braintrust, Browser Use. How do you ensure these third-party agents can't access sensitive customer data? What's the security model? "An Agent on Every Desk" Program Vercel launched a new program to help companies identify high-value use cases and build their first production AI agents. It provides consultations, reference templates, and hands-on support to go from idea to deployed agent
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About Latent Space: The AI Engineer Podcast

The podcast by and for AI Engineers! In 2024, over 2 million readers and listeners came to Latent Space to hear about news, papers and interviews in Software 3.0. We cover Foundation Models changing every domain in Code Generation, Multimodality, AI Agents, GPU Infra and more, directly from the founders, builders, and thinkers involved in pushing the cutting edge. Striving to give you both the definitive take on the Current Thing down to the first introduction to the tech you'll be using in the next 3 months! We break news and exclusive interviews from OpenAI, Anthropic, Gemini, Meta (Soumith Chintala), Sierra (Bret Taylor), tiny (George Hotz), Databricks/MosaicML (Jon Frankle), Modular (Chris Lattner), Answer.ai (Jeremy Howard), et al. Full show notes always on https://latent.space
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