BIOACTIVE

• The Science Behind how CBD Works in the Brain with guest Dr. Josh Kaplan

  In this conversation, Dr. Riley Kirk and Dr. Josh Kaplan delve into the complexities of cannabis research, particularly focusing on CBD and its therapeutic potential for conditions like epilepsy. Dr. Kaplan shares his journey into cannabis research, highlighting the significance of understanding CBD's mechanisms, the role of GPR55 in seizure management, and the challenges of dosing CBD effectively. They also discuss the entourage effect, the importance of personalized medicine, and the ongoing research into terpenes and their interactions with cannabinoids. The conversation emphasizes the need for further exploration in cannabis research to develop safe and effective therapies, especially for vulnerable populations like children. In this conversation, Josh Kaplan discusses the therapeutic potential of CBD, particularly in relation to traumatic brain injuries and neurodegenerative diseases. He emphasizes the safety of CBD compared to THC and explores its role in preventative treatments. The conversation also delves into ongoing clinical trials, particularly within the NFL, and the challenges faced in cannabis research, including dosing and the variability of individual responses to cannabinoids. Kaplan highlights the importance of understanding the entourage effect and the need for more personalized approaches in cannabis treatment. More about Dr. Kaplan: Dr. Kaplan is an Associate Professor in the Behavioral Neuroscience Program. His expertise is in neurophysiology, neuropharmacology, and animal behavior techniques, which his lab uses to study the therapeutic benefits and developmental consequences of cannabis in pre-clinical rodent models. His research seeks to optimize cannabinoid and terpene compositions to maximize benefit and minimize adverse consequences.  Dr. Kaplan has a strong passion for teaching and communicating science. His scientific writing specializes in the science of cannabis and its medicinal utility. He was included in High Times' 100 Most Influential People in Cannabis (2018) and Cannabis Newsletter's Top 100 (2021). Follow Dr.Kaplan’s research: https://wp.wwu.edu/kaplanlab/ Preorder my book Reefer Wellness! https://www.amazon.com/Reefer-Wellness-Understanding-Cannabis-Medicine/dp/0593847156 Seed Giveaway Thank you to Royal Queen Seeds and Last Green Valley Seeds for donating to this week's giveaway! To enter, fill out the form below, winners will be selected at random.  https://forms.gle/1vWtsBMGaux9x5Mf6 ✨ Want Exclusive Content? Join the Bioactive Patreon community for as little as $1/month to ask guests your burning questions, access exclusive content, and connect with Dr. Kirk one-on-one. www.Patreon.com/Cannabichem 🔔 Don’t forget to like, subscribe, and hit the notification bell for more expert insights into cannabis science, plant biology, and more! Keep up with Dr. Riley Kirk: https://www.bioactivepodcast.com/ https://www.youtube.com/@cannabichem https://instagram.com/cannabichem https://www.appliedpharmacognosy.org/ Timestamps: 00:00 Introduction to Cannabis Research and Its Importance 03:04 The Journey into CBD and Epilepsy 06:00 Understanding CBD's Mechanism of Action 08:54 The Role of GPR55 in Seizure Management 12:00 Exploring the Entourage Effect 14:53 Challenges in Dosing CBD for Multiple Conditions 18:02 Personalized Medicine and Endocannabinoid System 21:01 Researching Terpenes and Their Effects 24:01 Future Directions in Cannabis Research 34:12 The Therapeutic Potential of CBD 36:34 Traumatic Brain Injury and CBD Research 39:34 Clinical Trials and NFL Studies 48:01 Challenges in Cannabis Research 54:27 Dosing and Efficacy of CBD 01:00:24 The Entourage Effect and Individual Variability Learn more about your ad choices. Visit megaphone.fm/adchoices

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• The Science of the Dry and Cure Process with David Sandelman from Cannatrol

  In this episode of the Bioactive Podcast, Dr. Riley Kirk interviews David Sandelman from Cannatrol, delving into the intricate processes of drying and curing cannabis. David shares his journey into the cannabis industry, emphasizing the importance of controlling environmental conditions to achieve optimal drying and curing results. The conversation explores the science behind water activity, the significance of terpene retention, and the implications of traditional drying methods like the 60-60 method. David highlights the impact of drying rates on the final product and discusses the potential for enzymatic processes to enhance the curing experience. The episode concludes with insights into the variability of different cannabis cultivars and the importance of post-harvest practices in maximizing quality. In this conversation, Riley Kirk and David from Cannatrol delve into the intricacies of drying and curing cannabis, emphasizing the importance of strain specificity and the role of technology in enhancing the quality of cannabis products. They discuss methods for rehydrating overly dry cannabis, adjusting water activity for different products, and effective storage techniques for harvested cannabis. The conversation also touches on the significance of terpenes, the potential for using Cannatrol for other herbs, and the encouragement of experimentation with the technology. David shares insights on achieving consistent drying and curing processes, and the conversation concludes with practical advice for growers. Timestamps  00:00 Introduction to Drying and Curing Cannabis 03:46 The Science Behind Drying and Curing 12:50 Understanding Water Activity in Cannabis 14:43 The Importance of Terpene Retention 21:43 The 60-60 Method: Origins and Implications 26:31 The Rate of Drying and Its Effects 31:05 The Role of Enzymatic Processes in Curing 34:26 Understanding Strain Specificity in Drying and Curing 36:04 Rehydrating Cannabis: Enhancing Quality and Experience 38:41 Adjusting Water Activity for Different Products 41:43 Home Drying and Curing Techniques 43:49 Storing and Managing Harvests Effectively 45:37 The Importance of Terpenes in Cannabis 46:50 Exploring Other Uses for Cannatrol 49:40 Encouraging Experimentation with Cannatrol 51:40 Achieving Consistent Drying and Curing 53:40 Final Thoughts on Drying and Curing Process Learn more from Cannatrol: Instagram @Cannatrol   Website: https://www.cannatrols.com/ Seed Giveaway Make sure to comment the magical words on Instagram to be eligible to win some seeds from OR comment the same thing on the FREE Patreon post. Winners will be notified by next week and the next giveaway will be in two weeks when the next episode of Bioactive drops!  Preorder my book Reefer Wellness! https://www.amazon.com/Reefer-Wellness-Understanding-Cannabis-Medicine/dp/0593847156 ✨ Want Exclusive Content? Join the Bioactive Patreon community for as little as $1/month to ask guests your burning questions, access exclusive content, and connect with Dr. Kirk one-on-one. www.Patreon.com/Cannabichem 🔔 Don’t forget to like, subscribe, and hit the notification bell for more expert insights into cannabis science, plant biology, and more! Keep up with Dr. Riley Kirk: https://www.bioactivepodcast.com/ https://www.youtube.com/@cannabichem https://instagram.com/cannabichem https://www.appliedpharmacognosy.org/ Learn more about your ad choices. Visit megaphone.fm/adchoices

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• Homegrow Made Easy with Jordan River from Growcast

  In this conversation, Jordan River shares his journey into the cannabis industry, emphasizing the importance of home growing and the concept of Overgrow, which advocates for more individuals to cultivate their own plants. He discusses the therapeutic benefits of cannabis, the connection to nature, and the role of caregivers in supporting patients who cannot grow for themselves.  The conversation highlights the value of homegrown cannabis compared to dispensary products and the need for community support in the cannabis culture. In this conversation, Jordan River and Riley Kirk delve into the complexities of cannabis cultivation, emphasizing the importance of understanding individual patient needs and the unique responses to different cannabis strains. They discuss the intricate chemistry of cannabis, the significance of focus in cultivation, and the accommodations necessary for growers with physical disabilities.  The conversation also highlights community support for disabled growers, the best practices for transplanting and pot sizes, and the differences between soil choices for outdoor and indoor growing. Finally, they demystify the topic of nutrients, addressing common misconceptions and providing clarity for new growers. In this conversation, Jordan River and Riley Kirk delve into the intricacies of cannabis cultivation, discussing the importance of nutrients, the identification of male plants, and the benefits of feminized seeds. They explore the significance of testing cannabis for cannabinoids and terpenes, as well as effective methods for drying and curing cannabis. The episode concludes with insights on joining the grow community and accessing valuable resources for both novice and experienced growers. Keep up with Jordan & Growcast!  Instagram @Growcast Listen to Growcast on all streaming platforms: Apple, Spotify & All Streaming Platforms Become a member of Growcast: Growcast.com/Membership  Free Growing Guide: Growcast.com/Guide  X: @GrowcastPodcast   Seed Giveaway Make sure to follow @GrowItFromHome and @BioactivePodcast on Instagram to be eligible to win some seeds from OR comment the same thing on the FREE Patreon post. Winners will be notified by next week and the next giveaway will be in two weeks when the next episode of Bioactive drops!  Preorder my book Reefer Wellness! https://www.amazon.com/Reefer-Wellness-Understanding-Cannabis-Medicine/dp/0593847156 ✨ Want Exclusive Content? Join the Bioactive Patreon community for as little as $1/month to ask guests your burning questions, access exclusive content, and connect with Dr. Kirk one-on-one. www.Patreon.com/Cannabichem 🔔 Don’t forget to like, subscribe, and hit the notification bell for more expert insights into cannabis science, plant biology, and more! Keep up with Dr. Riley Kirk: https://www.bioactivepodcast.com/ https://www.youtube.com/@cannabichem https://instagram.com/cannabichem https://www.appliedpharmacognosy.org/ Timestamps: 00:00 Introduction and Personal Journey 04:47 The Concept of Overgrow 09:55 The Connection Between Cannabis and Nature 14:58 The Importance of Home Growing 19:57 The Role of Caregivers in the Cannabis Community 25:36 Understanding Cannabis Strains and Patient Needs 28:51 The Complexity of Cannabis and Individual Responses 30:56 Exploring the Unknowns of Cannabis Chemistry 33:55 The Importance of Focus in Cannabis Cultivation 34:22 Accommodating Growers with Physical Disabilities 38:00 Community Support for Disabled Growers 39:07 Transplanting and Pot Sizes for Optimal Growth 44:34 Soil Choices for Outdoor vs Indoor Growing 48:57 Demystifying Nutrients in Cannabis Cultivation 49:37 Understanding Nutrients in Plant Growth 55:49 Identifying Male Plants and Feminized Seeds 01:00:48 Learn more about your ad choices. Visit megaphone.fm/adchoices

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  1:12:50
• Choosing the Right Cannabis Seeds with Dan Nelson from Happy Valley Genetics

  In this episode of the Bioactive Podcast, Dr. Riley Kirk and Dan Nelson from Happy Valley Genetics discuss the importance of home growing cannabis and the various types of seeds available. They delve into the differences between photoperiod and autoflower seeds, the benefits of feminized seeds, and what beginner growers should consider when selecting seeds.  The conversation also touches on the evolution of cannabis genetics and the significance of disease resistance in cannabis cultivation. In this conversation, Dan Nelson and Riley Kirk delve into the intricacies of cannabis breeding, focusing on the importance of stable genetics, the challenges of ensuring high-quality seeds, and the differences between commercial and home growing. They discuss the significance of THC percentages versus terpene profiles, the impact of consumer education on the market, and practical tips for seed storage. The episode concludes with an exciting seed giveaway from Happy Valley Genetics, encouraging listeners to engage and grow their own cannabis plants. Seed Giveaway Make sure to follow @Happy_Valley_Genetics and @BioactivePodcast on Instagram to be eligible to win some seeds from Happy Valley Genetics OR comment the same thing on the FREE Patreon post. Winners will be notified by next week and the next giveaway will be in two weeks when the next episode of Bioactive drops!  Preorder my book Reefer Wellness! https://www.amazon.com/Reefer-Wellness-Understanding-Cannabis-Medicine/dp/0593847156 ✨ Want Exclusive Content? Join the Bioactive Patreon community for as little as $1/month to ask guests your burning questions, access exclusive content, and connect with Dr. Kirk one-on-one. www.Patreon.com/Cannabichem 🔔 Don’t forget to like, subscribe, and hit the notification bell for more expert insights into cannabis science, plant biology, and more! Keep up with Dr. Riley Kirk: https://www.bioactivepodcast.com/ https://www.youtube.com/@cannabichem https://instagram.com/cannabichem https://www.appliedpharmacognosy.org/ Didn’t win the giveaway but still want to buy seeds from Happy Valley Genetics or talk to Dan, head to https://happyvalleygenetics.com/ Chapters 00:00 Introduction to Home Growing and Seed Giveaway 07:28 Photoperiod vs. Autoflower: Key Differences 18:37 Feminized Seeds: What You Need to Know 25:06 Disease Resistance in Cannabis Genetics 39:10 Understanding High-Quality Genetics 46:13 Commercial vs. Home Growing: Seed Quality Learn more about your ad choices. Visit megaphone.fm/adchoices

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  58:29
• Cannabis Medical Cards with Dr. June Chin from Leafwell

  In this episode of the Bioactive Podcast, Dr. Riley Kirk speaks with Dr. June Chin, Chief Medical Officer at Leafwell, about the evolving landscape of medical cannabis.  They discuss the benefits of obtaining a medical card, the differences between medical and recreational cannabis, and the challenges faced by patients, including cost and accessibility. The conversation also delves into the sensitive topic of cannabis use and firearms, recent legal cases impacting this issue, and the importance of research in understanding the benefits of medical cannabis.  Dr. Chin shares insights on the process of obtaining a medical card and the implications for patients traveling with cannabis. In this conversation, Dr. June Chin and Riley Kirk discuss various aspects of medical cannabis, including legal considerations, impairment testing, education for medical professionals, the impact of federal prohibition, and personalized treatment plans.  They emphasize the importance of understanding cannabis strains, integrating cannabis with other medications, and clarifying regulations surrounding medical cards, particularly in Texas. The discussion highlights the need for education and awareness in the cannabis community. ✨ Want Exclusive Content? Join the Bioactive Patreon community for as little as $1/month to ask guests your burning questions, access exclusive content, and connect with Dr. Kirk one-on-one. www.Patreon.com/Cannabichem 🔔 Don’t forget to like, subscribe, and hit the notification bell for more expert insights into cannabis science, plant biology, and more! Keep up with Dr. Riley Kirk: https://www.bioactivepodcast.com/ https://www.youtube.com/@cannabichem https://instagram.com/cannabichem https://www.appliedpharmacognosy.org/ Keep up with Dr.June Chin and Leafwell: Follow Leafwell on Social media @leafwell_official  Follow Dr. June on IG at @DrJuneChin Head to Leafwell.com to learn more and check regulations in your state.  Head to my link on Leafwell for a discounted medical card:  https://leafwell.com/medical-card?utm_source=cannabichem  Learn more about your ad choices. Visit megaphone.fm/adchoices

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