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TechSurge: Deep Tech VC Podcast

Celesta Capital | Deep Tech Venture Capital Firm
TechSurge: Deep Tech VC Podcast
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  • Inside Microsoft's Trillion Dollar Playbook with Chief Strategy Officer Bobby Yerramilli-Rao
    Bobby Yerramilli-Rao, Chief Strategy Officer at Microsoft, joins TechSurge host Sriram Viswanathan to offer a rare glimpse into the strategic playbook of one of the world’s most powerful tech companies. Bobby shares how the company navigates today’s biggest technology paradigm shifts, placing bets with trillion-dollar implications. Touching on Microsoft’s AI strategy, OpenAI partnership, quantum computing, its approach to acquisitions, and much more, this candid and wide-ranging conversation is not to be missed. If you enjoy this episode, please subscribe and leave us a review on your favorite podcast platform. Sign up for our newsletter at techsurgepodcast.com for exclusive insights and updates on upcoming TechSurge Live Summits.
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  • Scaling the AI Era: Next-Gen Data Storage Solutions with Pure Storage CEO Charlie Giancarlo
    In this episode of TechSurge, host Sriram Viswanathan sits down with Charlie Giancarlo, Chairman and CEO of Pure Storage, to discuss the evolution and future of data storage in the digital age. Charlie shares insights from his career spanning his pivotal role in Cisco's success as a networking pioneer, to his leadership in transforming Pure Storage into a leader in innovative storage solutions.They explore the evolution of data center infrastructure, and the critical role of storage architecture in enabling AI and cloud technologies. Charlie also explains how Pure Storage's software-driven approach is creating new efficiencies and opportunities for enterprises, offering a compelling vision for a unified "data cloud" that breaks down data silos and unlocks new insights.This episode delves into the intersections of networking, compute, storage, and AI, providing an essential perspective for anyone interested in the future of technology infrastructure.If you enjoy this episode, please subscribe and leave us a review on your favorite podcast platform. Sign up for our newsletter at techsurgepodcast.com for exclusive insights and updates on upcoming TechSurge Live Summits.Links:Pure Storage Official Website: Explore Pure Storage's innovative data storage solutions. Pure Storage DataCharlie Giancarlo's Biography: Learn more about Charlie Giancarlo, Chairman and CEO of Pure Storage. ​Charlie GiancarloPortworx by Pure Storage: Discover Portworx, the Kubernetes data services platform acquired by Pure Storage. ​Wikipedia Portworx ASBIS – IT DistributorFlashBlade//EXA Announcement: Read about Pure Storage's FlashBlade//EXA, designed for high-performance computing and AI workloads. FlashBlade//EXA: The Future of AI and HPC Storage Performance
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  • Why AI Isn't Ready to Make Medicines
    Many in venture capital and biopharma are anointing artificial intelligence the savior of drug discovery—but what can AI actually do?In this eye-opening episode, Michael Marks sits down with Mike Nohaile, CEO of Prellis Biologics, to explore the hype versus reality in AI-enabled drug discovery. Mike details why, despite significant breakthroughs like AlphaFold and recent Nobel Prize win for computational protein design, fully AI-generated medicines still present challenges. He also discusses why we urgently need more effective medicines and details Prellis’ unique system which combines laser printed human organoids and an externalized human immune system with AI, enabling the discovery of fully human antibodies. If you enjoy this episode, please subscribe and leave us a review on your favorite podcast platform. Sign up for our newsletter at techsurgepodcast.com for exclusive insights and updates on upcoming TechSurge Live Summits.Links:Explore Prellis Biologicshttps://prellisbio.com/Understand AlphaFold, DeepMind’s AI model for predicting protein structureshttps://deepmind.google/alphafoldRead about the 2024 Nobel Prize in Chemistry https://www.nobelprize.org/prizes/chemistry/2024/press-release/ 
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  • Understanding the Elegant Math Behind Modern Machine Learning
    Artificial intelligence is evolving at an unprecedented pace—what does that mean for the future of technology, venture capital, business, and even our understanding of ourselves? Award-winning journalist and writer Anil Ananthaswamy joins us for our latest episode to discuss his latest book Why Machines Learn: The Elegant Math Behind Modern AI.Anil helps us explore the journey and many breakthroughs that have propelled machine learning from simple perceptrons to the sophisticated algorithms shaping today’s AI revolution, powering GPT and other models. The discussion aims to demystify some of the underlying mathematical concepts that power modern machine learning, to help everyone grasp this technology impacting our lives–even if your last math class was in high school. Anil walks us through the power of scaling laws, the shift from training to inference optimization, and the debate among AI’s pioneers about the road to AGI—should we be concerned, or are we still missing key pieces of the puzzle? The conversation also delves into AI’s philosophical implications—could understanding how machines learn help us better understand ourselves? And what challenges remain before AI systems can truly operate with agency?If you enjoy this episode, please subscribe and leave us a review on your favorite podcast platform. Sign up for our newsletter at techsurgepodcast.com for exclusive insights and updates on upcoming TechSurge Live Summits.Links:Read Why Machines Learn, Anil’s latest book on the math behind AIhttps://www.amazon.com/Why-Machines-Learn-Elegant-Behind/dp/0593185749Learn more about Anil Ananthaswamy’s work and writinghttps://anilananthaswamy.com/Watch Anil Ananthaswamy’s TED Talk on AI and intelligencehttps://www.ted.com/speakers/anil_ananthaswamyDiscover the MIT Knight Science Journalism Fellowship that shaped Anil’s AI researchhttps://ksj.mit.edu/Understand the Perceptron, the foundation of neural networkshttps://en.wikipedia.org/wiki/PerceptronRead about the Perceptron Convergence Theorem and its significancehttps://www.nature.com/articles/323533a0
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  • 21st Century Warfare: The Nexus of Technology, Economy, & National Security
    With global economic alliances shifting and new threats emerging, will the U.S. maintain its dominance in an increasingly complex world? From chips to cyberterrorist threats to cryptocurrency, battles for global dominance are no longer only fought on the battlefield—they're playing out in markets, boardrooms, and cyberspace. In this episode, we sit down with Juan Zarate, a key member of the post-9/11 Bush Administration team who architected how we combat terrorist financing and think about modern financial warfare.We explore how the U.S. has used its economic dominance as a powerful weapon—and whether countries like China and Russia are now using the same playbook to push back. Juan shares insights on the weaponization of the dollar, how financial crime networks are evolving in the digital age, and why strategies around cryptocurrency could either threaten or reinforce U.S. economic power.The conversation dives into the intersection of technology, economic, and national security strategy, tackling key issues like cyber threats, semiconductor supply chains, and the growing role of AI in financial security. Juan also introduces his latest venture, Consilient, which is pioneering federated AI to revolutionize the fight against financial crime.If you enjoy this episode, please subscribe and leave us a review on your favorite podcast platform. Sign up for our newsletter at techsurgepodcast.com for exclusive insights and information about upcoming TechSurge Live Summits.Links:Check out our video episodes on YouTubeFollow Celesta Capital on LinkedIn and XDiscover how K2 Integrity is shaping the future of financial crime prevention and cybersecurityhttps://www.k2integrity.comRead Juan Zarate’s Treasury’s War to explore the rise of financial warfare in global securityhttps://www.amazon.com/Treasurys-War-Unleashing-Financial-Warfare/dp/1610391152Explore Consilient’s groundbreaking approach to financial crime detection using federated AIhttps://www.consilient.comLearn how Coinbase is driving the future of cryptocurrency and digital financehttps://www.coinbase.com
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About TechSurge: Deep Tech VC Podcast

The TechSurge: Deep Tech VC Podcast explores the frontiers of emerging tech, venture capital, and business. For entrepreneurs, investors, tech professionals, or anyone interested in where technology is headed next. Presented by Celesta Capital, and hosted by Founding Partners Nic Brathwaite, Michael Marks, and Sriram Viswanathan. Email feedback and show ideas to [email protected]. Join us as we examine the next major tech cycle, uncover emerging global tech hubs, and analyze where VC investment dollars are headed. Tune in to hear directly from Silicon Valley leaders, daring new founders, and visionary thinkers. Past guests on the podcast and TechSurge Live summits include Kara Swisher, Vinod Khosla, former PepsiCo CEO Indra Nooyi, Micron CEO Sanjay Mehrotra, and others. Each discussion delves into the intersection of technology advancement, market dynamics, and the founder journey, offering insights into the vast opportunities and complex challenges ahead. Episode topics include AI, data center transformation, blockchain, cyber security, healthcare innovation, VC investment trends, tips for first-time founders, and more. New episodes release every two weeks. Visit techsurgepodcast.com for more details and to sign up for our newsletter and other content!
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