Razib Khan's Unsupervised Learning

On this episode of Unsupervised Learning Razib talks again with Washington Post columnist and repeat guest Shadi Hamid (listen to previous episodes). A native Pennsylvanian of Egyptian ethnic background and Islamic faith, Hamid completed his Ph.D. in politics at Oxford University. He is co-host of the Wisdom of Crowds podcast and website with Damir Marusic, and now the author of his own Substack and a recent book, The Case For American Power. Hamid is also the author of The Problem of Democracy: America, the Middle East, and the Rise and Fall of an Idea. , Temptations of Power: Islamists & Illiberal Democracy in a New Middle East and Rethinking Political Islam. Before moving the discussion to The Case For American Power, Razib asks Hamid about his current positioning on the American political landscape with the emergence of the hard-right during the second Trump administration. Hamid admits that during the "woke era" he wasn't sure about his place on the Left as a progressive due to his misgivings with racial identarianism, but with the rise of white nationalism on the Right and the executive decisions of the Trump administration Hamid finds himself more comfortable saying he is a progressive. Racism and the passions unleashed by the Israel-Palestine conflict since 10/7 have made Hamid reevaluate the virtues of some level of wokeness. Pivoting to foreign policy, Razib and Hamid discuss his new book, and its positioning within a political landscape that ranges from neconservatism, liberal internationalism and isolationism of all sorts. Despite Hamid's misgivings of some aspects of American culture and the nation's past political sins, he asserts (unlike the far Left) that overall America is a force for good, and that it should exercise its power to spread its vision of morality across the world. The Case For American Power is an attempt to articulate a liberal and progressive internationalist vision for 2025, decades after the failed Iraqi intervention. Hamid also addresses the sea-change on the progressive side of American politics when it comes to Israel, admitting he feels much freer to express skepticism or critiques of Israeli policy than he had in previous eras.

On this episode, Razib talks to Vishal Ganesan and Anang Mittal, two Indian-American Hindus who have been thinking about the role of their faith in the present, and past, of the American social landscape. Ganesan is a California-based attorney and writer who focuses on the history, identity, and representation of the Hindu diaspora in the United States. He is best known for his project "Hindoo History" and his writing on the "Frontier Dharma" platform, which attempts to conceptualize what an American, as opposed to Indian, "Hinduism" might look like. Anang Mittal is a DC-based political communications professional who recently worked for Senator Mitch McConnell. Mittal grew up in India before moving to the US at a young age about 25 years ago. Ganesan, in contrast, was born to an earlier generation of Indian immigrants to the US. He grew up north of Austin, TX. Though their perspectives differ, they both believe that Hinduism and Indian-American identity cannot simply be ported over with no changes into the American cultural landscape. The conversation is centered on two essays, Ganesan's The Meaning and Limits of "Hinduphobia" Discourse in the Diaspora and Mittal's What Hindu Americans Must Build. While Ganesan explores and articulates what it means to be Indian-American and Hindu today in America, and what might mean in the future, Mittal's argument is framed by a deep understanding of American history and how Hindus fit into the bigger arc of history. Razib, Ganesan and Mittal discuss the past, present, and potential future of Hindus and Indians, two separate categories, in America over the course of two hours. Their discussion was triggered by the online controversy over the fact that Vice President J. D. Vance's wife is a Hindu, and he has encouraged her to convert to his Roman Catholic religion (in which their children are being raised). But the discussion extends far beyond matters of contemporary politics, probing what it means to be American, and what it could mean to be a Hindu.

On this very special episode, Razib talks to paleoanthroplogists John Hawks and Chris Stringer. Hawks is a paleoanthropologist who has been a researcher and commentator in human evolutionary biology and paleoanthropology for over two decades. With a widely read weblog (now on Substack), a book on Homo naledi, and highly cited scientific papers, Hawks is an essential voice in understanding the origins of our species. He graduated from Kansas State University in 1994 with degrees in French, English, and Anthropology, and received both his M.A. and Ph.D. in Anthropology from the University of Michigan, where he studied under Milford Wolpoff. He is currently working on a textbook on the origins of modern humans in their evolutionary context. Hawks has already been a guest on Unsupervised Learning three times. Chris Stringer is affiliated with the Natural History Museum in London. Stringer is the author of African Exodus. The Origins of Modern Humanity, Lone Survivors: How We Came to Be the Only Humans on Earth and Homo Britannicus - The Incredible Story of Human Life in Britain. A proponent since the 1970's of the recent African origin of modern humans, he has also for decades been at the center of debates around our species' relationship to Neanderthals. In the 1980's, with the rise to prominence of the molecular model of "mtDNA Eve," Stringer came to the fore as a paleoanthropological voice lending support to the genetic insights that pointed to our African origins. Trained as an anatomist, Stringer asserted that the fossil evidence was in alignment with the mtDNA phylogenies, a contention that has been broadly confirmed over the last five decades. Razib, Hawks and Stringer discuss the latest work that has come out of Yuxian, China, and how it updates our understanding of human morphological diversity, and integrate it with the newest findings about Denisovans from whole genome sequencing. They talk about how we exist at a junction, with more and more data, but theories that are becoming more and more rickety in terms of explaining the patterns we see. Hawks talks about the skewing effect of selection on phylogenetic trees, while Stringer addresses the complexity of the fossil record in East Asia.

Today Razib talks to Sean Trende. He is a prominent American political analyst who currently serves as the Senior Elections Analyst for RealClearPolitics, a position he has held since 2010. He is also a Fellow at the American Enterprise Institute (AEI) and a lecturer at The Ohio State University, where he earned his Ph.D. in political science in 2023. Before transitioning to full-time political analysis, Trende practiced law for eight years at firms including Kirkland & Ellis LLP and Hunton & Williams LLP, holding a J.D. and M.A. from Duke University and a B.A. from Yale University. Known for his expertise in election forecasting, redistricting, and political demographics, he authored the book The Lost Majority (2012), co-authored The Almanac of American Politics 2014, and served as a court-appointed special master to redraw Virginia's legislative districts in 2021. Trende and Razib first talk about the elections in the fall of 2025 in Virginia and New Jersey, and what they tell us about the elections next year. They also discuss the election of Zohran Mamdani in New York City, and the rise of populism on the Left and Right. Razib asks Trende about why political commentary often assumes single-party rule is about to happen, only to be refuted by the reality of the opposition's resurgence once these claims are made. They also talk about Trende's distinctive personal background, and his perspective as a more centrist-libertarian commentator and professor in the political analyst field.

This week on the Unsupervised Learning Podcast, Razib talks to returning guest Alex Young of UCLA and Herasight. Trained originally as a mathematician, Young studied statistics and computational biology at the University of Cambridge before doing a doctorate in genomic medicine and statistics at the Wellcome Trust Centre for Human Genetics, University of Oxford, under Peter Donnelly. He also worked at deCODE Genetics in Reykjavik and at Oxford with Augustine Kong, developing methods in quantitative and population genetics. Razib and Young talk extensively about what we know about heritability and genomics in 2025, four years after their first conversation. In particular, they discuss what larger sample sizes, high-density genotype-arrays and whole-genome sequencing have told us about heritability and the ability to predict traits in individuals from their sequence. They discuss quantitative and behavioral traits like height, intelligence and risk of autism, and the differences between classical statistical genetical methods utilizing twins and modern molecular genomic techniques that attempt to fix specific physical markers as causal factors in characteristics of interest. In addition to his academic work, Young has also been consulting for the polygenic embryo-screening company Herasight, working on cutting-edge methods for genomic prediction in the context of in vitro fertilization. They dig deep into the new method Young and colleagues worked on that helps democratize embryo selection using genomics, ImputePGTA.